The preterm parturition syndrome

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Prevention of preterm parturition.

In the United States, the annual rate of preterm births (before 37 weeks of gestation) reached a peak of 12.8% in 2006 and was 11.7% in 2011.1 The rate in the United States remains nearly twice the rate in European nations.2 Premature birth in the United States accounts for 35% of deaths in the first year of life3,4 and estimated annual costs exceeding $26 billion.5 Rates of death in the first ...

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Inflammatory processes in preterm and term parturition.

A role for the pro-inflammatory cytokines interleukin (IL)-1beta, IL-6, IL-8 and tumor necrosis factor alpha (TNF-alpha) is evident in term and preterm delivery, and this is independent of the presence of infection. All uterine tissues progress through a staged transformation near the end of pregnancy that leads from relative uterine quiescence and maintenance of pregnancy to the activation of ...

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Microbiome in parturition and preterm birth.

Preterm parturition is a one of the most significant global maternal-child health problem. In recent years, there has been an explosion in reports on a role for microbiomes (i.e., a microbial biomass) on a plethora of physiologic and pathologic human conditions. This review aims to describe our current understanding of the microbiome and its impact on parturition, with particular emphasis on pr...

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A Role for the Liver in Parturition and Preterm Birth.

Neither the mechanisms of parturition nor the pathogenesis of preterm birth are well understood. Poor nutritional status has been suspected as a major causal factor, since vitamin A concentrations are low in preterm infants. However, even large enteral doses of vitamin A from birth fail to increase plasma concentrations of vitamin A or improve outcomes in preterm and/or extremely low birthweigh...

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Respiratory distress syndrome in the preterm neonate

As in the adult with acute lung injury and acute respiratory distress syndrome, the use of lung-protective ventilation has improved outcomes for neonatal lung diseases. Animal models of neonatal respiratory distress syndrome and congenital diaphragmatic hernia have provided evidence that ‘gentle ventilation’ with low tidal volumes and ‘open-lung’ strategies of using positive end-expiratory pres...

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ژورنال

عنوان ژورنال: BJOG: An International Journal of Obstetrics & Gynaecology

سال: 2006

ISSN: 1470-0328

DOI: 10.1111/j.1471-0528.2006.01120.x